提高对传染病的免疫力

自COVID-19大流行以来, terms such as ‘immunity’ and ‘protection’ have become ever-present in our daily lives over the last couple of years. 澳门第一赌城在线娱乐已经更加清楚明天会带来什么, giving new significance to preventing and protecting against infectious diseases.

The pandemic has also dramatically accelerated the science behind vaccines and disease prevention, 澳门第一赌城在线娱乐很荣幸能在这方面发挥领导作用. Now, 通过遵循这一科学并共同努力, we must continue to transform how we protect people – and especially the most vulnerable in society – from infectious diseases.

At the ISIRV OPTIONS/International RSV Symposium congresses in September, 然后是10月的IDWeek, we will have the opportunity to reflect on how far we have come and on our ongoing commitment to protecting millions of people worldwide from diseases such as COVID-19, 流感和呼吸道合胞病毒(RSV).

全球传染病负担
这项任务至关重要, 因为这些疾病的负担很高, 对儿童的影响尤为严重. For example, there are approximately one billion influenza cases globally every year,¹ 儿童的疾病负担最高, 每年有20-30%的人被感染, 与5-10%的成年人相比.^2,3

Similarly, RSV is a common respiratory virus that is contracted by 90% of children by the age of two.^4,5 虽然RSV通常产生轻微的, 冷若症状, in more serious cases it can progress to lower respiratory tract infections, 如细支气管炎和肺炎.^6,7,8

In some babies, particularly those born prematurely or those two years or younger with heart or lung conditions, 发生这些严重感染的风险更高, 会带来危及生命的后果.^9,10 But the reality is that any infant – whether they are born at term or prematurely, or have other health conditions – can be hospitalised in their first RSV season, 许多住院的婴儿被认为是健康的.^11,12

It is not enough to just treat these diseases when they strike – indeed, 比如呼吸道合胞病毒, 没有具体的治疗方法. 相反，澳门第一赌城在线娱乐必须首先防范它们. 预防至关重要, particularly in a health system that has already been put under huge strain by the added pressure of a pandemic on top of a considerable existing infectious disease burden.

推进疾病预防
Disease prevention is something that we’re intently focused on through decades of experience in antibody development.

This expertise is the foundation of the complementary approach that we are taking, optimising the potential of both vaccines and antibodies to provide long-lasting immunity, 以澳门第一赌城在线娱乐在这个领域率先创新的传统为基础. It was something that enabled us to be successful in helping to respond to the pandemic, and it will continue to be integral in delivering greater protection in influenza and RSV, 哪里也有类似的行动需要.

For example, in influenza, vaccinating 70% of children aged between approximately one and six years of age could help reduce community transmission of flu, 并通过减少传播为他人提供间接保护.^13,14

Childhood vaccination programmes like the one in the UK have already demonstrated both feasibility and impact of this approach, 澳门第一赌城在线娱乐正在向英国等国家提供儿科疫苗, 支持爱尔兰和芬兰在这些努力中扩大保护.^15,16,17,18

In RSV, meanwhile, we are working to build on our longstanding heritage and help improve prevention of the disease for infants in the future – not just for those at high-risk, 而是针对所有可能感染呼吸道合胞病毒的婴儿.

解决全球健康和治疗不平等问题
While we don’t know when the next pandemic may emerge or what it will be, we are committed to playing a central role in addressing current and future pandemic and endemic diseases.

The COVID-19 pandemic tested our health systems to their limits but through ground-breaking collaborations, 当地合作伙伴, 商业倡议和先进制造, 澳门第一赌城在线娱乐正在帮助确保它们能够抵御未来潜在的冲击. 

We want to make better disease prevention and vaccines a lasting legacy of the pandemic, 帮助保护世界各地的人们免受传染病的侵害.